| Southampton FC vs. Bolton Wanderers | 10-17-2026
Saturday
3:00 PM | St. Mary's Stadium in Hants, United Kingdom | View Tickets |
| West Ham United FC vs. Southampton FC | 10-24-2026
Saturday
TBD | London Stadium At Queen Elizabeth Olympic Park in London, United Kingdom | View Tickets |
| Southampton FC vs. Derby County FC | 11-21-2026
Saturday
TBD | St. Mary's Stadium in Hants, United Kingdom | View Tickets |
| Sheffield United FC vs. Southampton FC | 11-24-2026
Tuesday
TBD | Bramall Lane in Sheffield, United Kingdom | View Tickets |
| Wolverhampton Wanderers vs. Southampton FC | 12-5-2026
Saturday
TBD | Molineux Stadium in Wolverhampton, United Kingdom | View Tickets |
| Southampton FC vs. Burnley FC | 12-9-2026
Wednesday
TBD | St. Mary's Stadium in Hants, United Kingdom | View Tickets |
| Southampton FC vs. Blackburn Rovers | 12-19-2026
Saturday
TBD | St. Mary's Stadium in Hants, United Kingdom | View Tickets |
| Southampton FC vs. Cardiff City FC | 1-1-2027
Friday
TBD | St. Mary's Stadium in Hants, United Kingdom | View Tickets |
| Queens Park Rangers FC vs. Southampton FC | 1-23-2027
Saturday
TBD | Loftus Road Stadium in London, United Kingdom | View Tickets |
| Southampton FC vs. West Bromwich Albion FC | 1-26-2027
Tuesday
TBD | St. Mary's Stadium in Hants, United Kingdom | View Tickets |
| Southampton FC vs. Preston North End | 1-30-2027
Saturday
TBD | St. Mary's Stadium in Hants, United Kingdom | View Tickets |
| Southampton FC vs. Norwich City FC | 2-17-2027
Wednesday
TBD | St. Mary's Stadium in Hants, United Kingdom | View Tickets |
| Southampton FC vs. Watford FC | 3-6-2027
Saturday
TBD | St. Mary's Stadium in Hants, United Kingdom | View Tickets |
| Southampton FC vs. Wolverhampton Wanderers | 3-16-2027
Tuesday
TBD | St. Mary's Stadium in Hants, United Kingdom | View Tickets |
| Southampton FC vs. Charlton Athletic FC | 3-20-2027
Saturday
TBD | St. Mary's Stadium in Hants, United Kingdom | View Tickets |
| Southampton FC vs. Lincoln City FC | 4-10-2027
Saturday
TBD | St. Mary's Stadium in Hants, United Kingdom | View Tickets |
| Millwall FC vs. Southampton FC | 4-17-2027
Saturday
3:00 PM | The Den - Bermondsey in Southwark, United Kingdom | View Tickets |
| Southampton FC vs. Birmingham City FC | 4-20-2027
Tuesday
TBD | St. Mary's Stadium in Hants, United Kingdom | View Tickets |
| Burnley FC vs. Southampton FC | 4-24-2027
Saturday
TBD | Turf Moor in Burnley, United Kingdom | View Tickets |
| Southampton FC vs. Sheffield United FC | 5-1-2027
Saturday
TBD | St. Mary's Stadium in Hants, United Kingdom | View Tickets |
